Vignettes using VRS
- Harmonizing ClinVar by VRS identity — Republishing all of ClinVar in the GKM so every variant carries a VRS identity and every classification is a structured VA-Spec statement, letting you join ClinVar to any VRS-aware dataset by identity.
- Sharing oncogenicity knowledge with GA4GH GKM — CIViC represents oncogenicity classifications and their supporting evidence with GA4GH GKM for exchange, reuse, and workflows such as ClinVar submission.
- Making personal genomic knowledge auditable so AI can be trusted, not just believed — Individual-Centric Genomics Platform JPN uses VRS, Cat-VRS, and VA-Spec to make personal genomic knowledge traceable and auditable for people and AI tools.
- Identifying unique variants across sources with VRS — Using VRS digests to deduplicate BRCA variants pulled from ClinVar, gnomAD, LOVD, and the literature.