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Workflow Execution Service (WES) API

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The Global Alliance for Genomics and Health is an international coalition, formed to enable the sharing of genomic and clinical data.

Cloud Work Stream

The Cloud Work Stream helps the genomics and health communities take full advantage of modern cloud environments. Our initial focus is on “bringing the algorithms to the data”, by creating standards for defining, sharing, and executing portable workflows.

We work with platform development partners and industry leaders to develop standards that will facilitate interoperability.

What is WES?

The Workflow Execution Service API describes a standard programmatic way to run and manage workflows. Having this standard API supported by multiple execution engines will let people run the same workflow using various execution platforms running on various clouds/environments. Key features include:

API Definition

See the human-readable Reference Documentation and the OpenAPI YAML description. You can also explore the specification in the Swagger Editor.

All documentation and pages hosted at ‘’ reflect the latest API release from the master branch. To monitor the latest development work, add ‘preview/<branch>’ to the URLs above (e.g., ‘<branch>/docs’). To view the latest stable development API specification, refer to the develop branch.

Use Cases

Use cases include:

Possible Future Enhancements

How to Contribute Changes


If a security issue is identified with the specification, please send an email to detailing your concerns.


See the LICENSE.

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